How Do I Interpret Disaccharidase Biopsy Results?

It may be beneficial for you to have a copy of your/your child’s disaccharidases small bowel biopsy results. You can ask your doctor or the medical records department of your child’s medical practice for a copy.


Classic CSID disaccharidases small bowel biopsy results are as follows:


Your/your child’s levels may differ from the above since there are differences in severity of CSID and the degree to which each patient has problems with starch. Almost all patients will have significant problems with sucrose. Some patients with CSID can tolerate typical amounts of starches in their diet. These patients would most likely have normal amounts of maltase and palatinase (isomaltase). Some patients with CSID will tolerate no starch at all. These patients would probably show low levels of maltase and palatinase (isomaltase). Knowing lactase levels is also valuable because dairy can be an important source of calories for patients who are not lactose intolerant. Some patients will have normal lactase levels, while others are deficient in lactase. Knowing  disaccharidase levels can help in developing the best diet for each patient’s unique situation. Note that the chart below shows abnormal ranges for labs in the United States only. Consult the CSID patient’s individual lab report for what is considered abnormal for the particular lab that conducted his/her disaccharidase testing.


Sucrase: Abnormal Range is less than 25
Maltase: Abnormal Range is less than 100
Palatinase (Isomaltase): Abnormal Range is less than 5
Lactase: Abnormal Range is less than 15